Pengaruh Gambir (Uncaria gambir R.) Terhadap Penyembuhan Luka Bakar Pada Mencit Putih (Mus musculus L.) Jantan

Nelsy Sucidayana Sumosa, - Efrizal, Resti Rahayu

Abstract

An experimental study on the effect of Gambier (Uncaria gambir R.) on burned skin of male white mice (Mus musculus L.) was conducted at The Animal Physiology Laboratory Andalas University. This experiment used Complete Random Design (CDR) consisted of five treatments, i.e: 0.00%, 0.25%, 0.50%, 0.75%, 1.00% and five replication with the observation lasted for 15 days. The results showed that Gambier gave significantly different effects (p = 0.004) on both the percentage of healing and the wound recovery. The highest percentage of wound healing was 94.783% and the largest diameter of wound recovery was 9.436 mm obtained at 0.50%  at 8 days.

Keyword: Uncaria gambir, burned skin, wound recovery.

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References

Agoes, A. 2010. Tanaman Obat Indonesia. Buku ke- 3. Salemba Medika. Jakarta.

Anggraini, T., A. Tai, T. Yoshino, T. Itani. 2011. Antioxidative Activity and Catechin Content of Four Kinds of Uncaria gambir Extracts from West Sumatra, Indonesia. African Journal of Biochemistry Research 5(1): 33-38.

Apriyanti. 2009. Burn Foundation Indonesia. www.lukabakar.Or.id. 23 Oktober 2013

Fife, B. N. D. 2004. The coconut Oil Miracle. Penguin Book inc. USA.

Friedrick, P. 2003. Wound Healing Studies in Human Volunteers. http:// www. woundcare. org/news.html. 20 Januari 2014.

Hasym, N. 2012. Formulasi dan Uji Efektivitas Gel Luka Bakar Ekstrak Daun Cocor Bebek (Kalanchoe pinnata L.) Pada Kelinci (Oryctolagus cuniculus). Majalah Farmasi dan Farmakologi 16(2).

Li, K., Y. Diao, H. Zhang, S. Wang, Z. Zhang, B. Yu, S. Huang, H. Yang. 2011. Tannin extract from immature fruits of Terminalia chebula Fructuz Retz. promote cutaneous wound healing in rats. BMC Complementary & Alternative Medicine 11: 86-95.

Moenadjat, F. 2009. Luka Bakar Masalah dan Tatalaksana. Fakultas Kedokteran Universitas Indonesia. Jakarta.

Naibaho, O. H., P. V. Y. Yamlean, W. Wiyono. 2013. Pengaruh Basis Salep Terhadap Formulasi Sediaan Salep Ekstrak Daun Kemangi (Ocimum sanctum L.) Pada Kulit Punggung Kelinci Yang Dibuat Infeksi Staphylococcus aureus. Pharmacon Jurnal Ilmiah Farmasi – UNSRAT. Manado.

Nakagawa, K. 2005. Antioxidative Activity of 3-O-Octanol-(+)-Catechin, a Newly Synthesized Catechin, in Vitro. Department of Food and Nutrition, Kyoto Women’s University. Japan Journal of Health Science 51(4): 492- 496.

Nazhifah. 2012. Uji Sensitivitas Isolat Bakteri Dari Pasien Luka Bakar di Bangsal Luka Bakar RSUP DR. M. Djamil Padang. [Skripsi]. Universitas Andalas. Padang.

Othman, N., D. Kendrick. 2010. Epidemiology of burn in the East Mediterranean Region a systematic review. Public Health 10: 83-93.

Sinko, P. J. 2006. Martin’s physical pharmacy and pharmaceutical sciences physical chemical and biopharmaceutical principles in the pharmaceutical sciences. 5th edition. Lippincolt Williams and Wilkins. Philadelphia.

Wijaya, A. 2012. Pengaruh Pemberian Berbagai Coconut Oil Secara Topikal Terhadap Penyembuhan Luka Bakar kimiawi Pada Kulit Tikus Putih (Rattus norvegicus) Terinduksi Asam Sulfat. FKIK (Pendidikan Dokter) 8 (9): 1-11

Yulianti, O. N. 2009. Kajian Aktivitas Antioksidan dan Antimikroba Ekstrak Biji, Kulit Buah, Batang, dan Daun Tanaman Jarak Pagar (Jatropha curcas L.).[Skripsi]. Institut Pertanian Bogor. Bogor.

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